Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0003rdr14 | Development of the Reproductive Axis | REDR1994

Inhibin and activin in embryonic and fetal development in ruminants

Jenkin G , McFarlane J , de Kretser DM

Inhibin, activin and follistatin are protein hormones with diverse physiological roles. The involvement of inhibin in the regulation of pituitary FSH production and secretion in adult males and non-pregnant females is well established. However, it is unlikely that inhibin plays a similar role in pregnancy in ruminants. Inhibin and activin molecules show a high degree of structural similarity to potent growth and differentiation factors of the transforming growth factor β ...

bp0001redr6 | (1) | REDR1980

The effect of intrauterine gonadectomy on fetal and neonatal gonadotrophin secretion in the lamb

Bremner WJ , Cumming IA , Williams DM , de Kretser DM , Lee VWK

Summary. In Exp. 1, sheep fetuses (2 male and 3 female) were gonadectomized between Days 70 and 120 of gestation and their blood LH and FSH levels were compared to those of control animals (4 male, 6 female) at regular times during the first year after birth. In Exp. 2. fetuses (3 male and 5 female) were gonadectomized between Days 50 and 60 of gestation and gonadotrophin levels at Day 90 of gestation were compared to those of control fetuses of the same age. ...

bp0001redr11 | (1) | REDR1980

Effects of LH-RH infusion, castration and cryptorchidism on gonadotrophin and testosterone secretion in developing rams

Lee VWK , Bremner WJ , Cumming IA , de Kretser DM , Findlay JK

Summary. The relationship between the pituitary gland and testis in rams was studied from birth to sexual maturity. The concentrations of LH, FSH and testosterone increased between 5 and 7 weeks of age; the rise was not correlated with any specific cytological change in the testis. An augmented pituitary response to LH-RH was demonstrated as levels of gonadotrophin increased. It is unclear whether this change in sensitivity plays a role in initiation of the pu...

bp0002rdr13 | Inhibin | REDR1990

Inhibin in rams

Clarke IJ , Tilbrook AJ , Galloway DB , Earl CR , Findlay JK , de Kretser DM

Abstract unavailableKeywords: inhibin; male; reproduction; gonadotrophins; FSH© 1991 Journals of Reproduction & Fertility Ltd...